This is the story of Lincoln Loud who is the only boy and middle child in a family of 11 kids. His 10 sisters give him unwanted make-overs, quarrel with him over the remote and generally cause havoc in the house. Lincoln's best friend Clyde is the only child in his family and is jealous of Lincoln's large family, and tries to get involved in all their activities. Clyde also has a crush on Lori, Lincolns' oldest sister.